Genolife

Detection of the virus of the Human Papilloma Virus

At Genolife we perform human papillomavirus detection from cervical, urethral, buccal, liquid cytology and kerosene blocks. This test is performed by identifying the HPV DNA present in the biological sample. The technique used is the Polymerase Chain Reaction (PCR).

HPV Screening in Women

Esta prueba se recomienda a mujeres con vida sexual activa, que desean cuidarse de posibles infecciones oncogénicas responsables del cáncer cervicouterino. Esta prueba se puede solicitar directamente en el laboratorio o con tu médico de confianza.

HPV Screening in Men

A man infected with human papillomavirus (HPV) can infect his sexual partner even if he has no visible symptoms of the condition on his genitals. This test can be ordered directly from the laboratory.

Identification of HPV viral subtypes

Actualmente hay varios tipos de pruebas de VPH es importante saber cuáles tienen utilidad clínica. Las pruebas que solo detectan la presencia del VPH, no tienen relevancia clínica ya que no identifican el riesgo y por lo tanto no sabes si hay peligro o no y como mencionamos, el 90% de las personas sexualmente activas alguna vez van a tener algún tipo de VPH, lo importante es saber cuál. Hay pruebas de VPH que identifican alto riesgo y bajo riesgo, estas pruebas agrupan en 2 subtipos virales que indican si tienes un tipo de alto o bajo riesgo sin indicar el subtipo específico, esta prueba tiene utilidad clínica media.

En Genolife realizamos la identificación específica de 44 subtipos virales, esta prueba tiene una alta utilidad clínica ya que tu medico sabrá con mayor precisión el riesgo específico que presentas, además si hay algún síntoma, coinfecciones y/o factores de riesgo tu médico podrá realizar un seguimiento y tratamiento personalizado.

En Genolife se identifican 21 subtipos del VPH de Alto riesgo (AR): 16, 18, 26, 31, 33, 34, 35, 39, 45, 51, 52, 53, 56, 58, 59, 66, 67, 68, 70, 73, 82, y los 23 subtipos VPH de Bajo riesgo (BR): 6, 11, 13, 32, 40, 42, 43, 44, 54, 55, 57, 61, 62, 64, 69, 71, 72, 81, 83, 84, 87, 89 y 90.

Human Papillomavirus Pathogenicity Guideline

VPH de Alto Riesgo (AR)

Pathogenicity
HPV subtypes
Very high risk

16, 18, 31, 33, 45 y 58

These viral subtypes are associated with the following pathologies: malignant mucosal lesions, squamous lesions, cervical intraepithelial neoplasia, cervical adenocarcinoma, malignant cervical neoplasms, squamous cell cancer, cervical adenocarcinoma and cervical cancer.

High risk

35, 39, 51, 52, 56, 59, 66, 68 y 70

These viral subtypes are associated with the following pathologies: cervical intraepithelial neoplasia, cervical carcinoma and malignant mucosal lesions.
Probable high risk

26, 34, 53, 67, 73 y 82

These viral subtypes are related to the following pathologies: Malignant mucosal lesions.

Low Risk (BR) HPV

Pathogenicity
HPV subtypes
Low risk

6, 11, 55, 64 y 69

These viral subtypes are associated with the following pathologies: recurrent respiratory papillomatosis, conjunctival papillomas/carcinomas, low-risk cervical intraepithelial neoplasia, verrucous carcinoma, benign mucosal lesions, genital warts in men and women, laryngeal papillomas.

Probable low risk

13, 32, 40 y 43

Estos subtipos virales están relacionados con las siguientes patologías: Lesiones de mucosa benigna y carcinoma verrucoso.

Very low risk

42, 44, 54, 57, 61, 62, 71, 72, 81, 83, 84, 87, 89 y 90

These viral subtypes are related to the following pathologies: Low-risk lesions in the oral or genital mucous membranes.

What is HPV?

El Virus del Papiloma Humano o VPH es el virus más común del aparato reproductor masculino y femenino.  La mayoría de las sexually active women and men will become infected at some point in their lives, and some people may have recurrent infections. This virus is found in the mucous membranes. 

Most men and women become infected soon after the onset of sexual activity. HPV is transmitted through sexual or skin-to-skin contact.  Mujeres embarazadas pueden infectar al recién nacido at birth only if natural childbirth in eyes, nose and/or throat.

There are many types of HPV and many of them do not cause problems. HPV infections usually clear up without any intervention within a few months after they are contracted, and around the 90% disappears after 2 years. However, a percentage of infections by some HPV viral subtypes can persist and become cancer.

How HPV infection leads to cancer

Although most HPV infections can be of non-oncogenic viral subtypes and go away on their own, all individuals are at risk for infection with the viral subtypes High-risk oncogenic HPV (16, 18, 31, 33, 45, 52 and 58) and become complicated, progressing to precancerous lesions that may progress to invasive cancer. 

Cervical cancer is the disease directly related to an infection with the viral subtypes of HPV known as “cervical cancer.“high-risk“.  Infection with some types of HPV can also cause other types of cancer such as anal, vulvar, vaginal, penile, and oropharyngeal cancers, which are preventable with the detection of the infection.

The types of Non-oncogenic HPV (en especial el 6 y el 11) pueden provocar verrugas genitales y papilomatosis respiratoria (enfermedad caracterizada por la aparición de tumores en las vías respiratorias que van de la nariz y la boca hasta los pulmones). Si bien esta enfermedad rara vez es mortal, el número de very high relapse. Genital warts are very common and very contagious.

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