Hereditary cancer is a disease that occurs when a mutation in the genes is inherited.
Between 5% and 10% of cancers are hereditary.
The BRCA1 and BRCA2 genes are two examples of genes that, if inherited, increase the risk of developing breast cancer.
Hereditary cancer syndromes are characterized by:
The appearance of the same type of cancer in several family members.
The development of the disease at an earlier age than normal.
The appearance of cancer on the sides of the body when the affected organ is even.
The hereditary cancer panel is a genetic test that is used to detect whether a person has the mutation and to assess the risk of cancer.
ACVR1, AKT1, AKT2, ALK, APC, APOBEC3B, AR, ATM, ATP1A1, ATP2B3, ATR, AXIN2, BAP1, BARD1, BLM, BMPR1A, BRAF, BRCA1, BRCA2, BRIP1, BTK, BUB1B, CACNA1D, CALR, CARD11, CCNE1, CD79A, CD79B, CDC73, CDH1, CDH10, CDK4, CDKN1B, CDKN1C, CDKN2A, CEBPA, CFTR, CHD4, CHEK2, CLTCL1, CSF3R, CTCF, CTNNA1, CXCR4, CYLD, DDR2, DDX41, DICER1, DIS3L2, DKC1, DNMT3A, EGFR, EPAS1, EPCAM, ERBB2, ERBB3, ERBB4, ERCC2, ERCC3, ERCC4, ERCC5, ESR1, ETNK1, ETV6, EXT1, EXT2, EZH2, FADD, FAN1, FANCA, FANCB, FANCC, FANCD2, FANCE, FANCF, FANCG, FANCI, FANCL, FANCM, FAT1, FCGR2B, FEN1, FGFR2, FGFR4, FH, FLCN, FLT3, FLT4, FOXA1, FOXL2, GALNT12, GATA1, GATA2, GNA11, GNAQ, GNAS, GPC3, HIF1A, HMGA1, HNF1A, HOXB13, HRAS, IDH1, IDH2, IKBKB, IL6ST, IL7R, INSR, JAK1, JAK3, JUN, KCNJ5, KDR, KIT, KLF4, KRAS, LMO1, LZTR1, MAP2K1, MAP2K2, MAPK1, MAX, MDM2, MDM4, MED12, MEN1, MET, MITF, MLH1, MLH3, MPL, MRE11, MSH2, MSH3, MSH6, MTOR, MUTYH, MYCL, MYCN, MYD88, MYOD1, NBN, NCOR2, NF1, NF2, NFE2L2, NFKBIE, NKX2-1, NOTCH2, NRAS, NSD1, NSD2, NT5C2, NTHL1, NTRK1, PALB2, PAX5, PDGFRA, PHOX2B, PIK3CA, PLCG1, PMS1, PMS2, POLD1, POLE, POLQ, POT1, PPM1D, PPP2R1A, PPP6C, PREX2, PRF1, PRKAR1A, PRSS1, PTCH1, PTEN, PTK6, PTPN11, PTPN13, RAC1, RAD50, RAD51C, RAD51D, RAF1, RB1, RECQL4, REL, RET, RFWD3, RHOA, RPL10, RPL5, RUNX1, SBDS, SDHA, SDHAF2, SDHB, SDHC, SDHD, SETBP1, SF3B1, SLX4, SMAD4, SMARCA4, SMARCB1, SMARCE1, SMO, SOX2, SPOP, SRC, SRSF2, STAT3, STK11, SUFU, TBX3, TERC, TERT, TGFBR2, TMEM127, TP53, TP63, TRAF7, TRRAP, TSC1, TSC2, TSHR, U2AF1, USP8, USP9X, VHL, WAS, WRN, WT1, XPA, XPC, XPO1, XRCC2, ZFHX3, ZNF331.
Anyone can inherit and pass on genetic changes that can increase the risk of cancer. Anyone with a family history of cancer concerns, including breast and ovarian cancer, should consider genetic testing to determine cancer risk.
Hereditary cancer testing is a type of genetic test that can help you and your doctor determine if you have an increased risk of developing cancer due to certain types of genetic changes that may have been passed down through the generations in your family.
Knowing if you are at increased risk for cancer will allow you to make medical decisions that could save your life.
You and your doctor can work together to create a personalized plan to reduce your risk of developing cancer or increase the likelihood of detecting cancer at an earlier, more treatable stage.
Here at Genolife we offer you a personalized plan to reduce risks and make early detection.
Hereditary Cancer Panel
- Digital and in-app reporting
- Appointment with an interpreter